Researched
Alzheimer's disease described
Alois Alzheimer reported in 1906 a woman whose memory loss came with plaques and tangles in her brain, defining the disease later named after him.
Open in the interactive tree →His patient Auguste Deter died in 1906, and silver staining of her brain showed clumps outside cells and twisted fibres inside them. These two hallmarks still guide diagnosis and drug trials.
Prerequisites
Unlocks
- Alzheimer's antibody drugs2023
- Alzheimer's and brain declineopenThe plaques and tangles Alzheimer described define the leading dementia