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Researched1897 · Industrial Age (1700 – 1900)

Life / Biology & Genetics

Enzymes: life without cells

Eduard Buchner fermented sugar with a cell-free yeast extract in 1897, showing that chemical catalysts, not a vital force, drive life's reactions.

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His pressed yeast juice made alcohol without a single living cell, which won him the 1907 Chemistry Nobel Prize. James Sumner crystallised the first enzyme, urease, in 1926 and showed that enzymes are proteins.

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